research paper on skin diseases

Assessing skin disease and associated health-related quality of life in a rural Lao community. Cytokine profile for confirmed PV cases showed direct evidences for involvement of T cell responses. AP: assisted in the conception and designing of the study and acquisition of the data. Scores ranged from 0 to 24 with a median score of 4, with 17% (20 participants) of patients completing the DLQI scoring over 10 (Table 3). Although other forms of the condition may exist, they are extremely rare and are not well-characterized. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. When you are sleeping the female itch mite is wide awake. Found inside – Page iProvides the latest information on imaging technologies and transdermal delivery in skin disorders This important, timely book covers the latest understanding about today's major skin disorders, the development of imaging technologies for ... PubMed  Different machine learning techniques are applied to predict the various classes of skin disease. Later dosage adjustments should be made on the basis of monitoring of both plasma drug (and possible metabolite) concentrations, and the efficacy and tolerability of the drugs. Penn Dermatology is known worldwide for its long history, exceptional leadership and significant work in conducting clinical research and clinical trials involving the skin, hair and nail diseases. NIAID scientists evaluate each case and may decide to use wet wrap therapy to bring the condition under control. Translating the science if the quality of life into practice: what do dermatology life quality index scores mean? 2008;158:334–8. J. Pharm. 1,000 skin or skin-related illnesses, a pattern dominated by a few conditions accounting for most of the skin disease burden. Bacterial skin infection is very painful and the skin becomes red and usually warm to touch. Phathammavong O, Ali M, Phengsavanh A, et al. 1), acne (10%; 19 people), scabies infestation (9%; 16 people), melasma (8%; 14 people) and pityriasis versicolor (4%; 8 people). The most common conditions seen were: acne, eczema, scabies, urticaria and tinea corporis. Eczematous Skin Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Eczematous Skin Diseases in a compact format. Int. Some people develop scaly patches, skin tags, or bright red or purple raised bumps (cherry angiomas), which might be bothersome but are usually harmless. Skin diseases are, however, a significant problem all over the world. 2012;51(5):579–87. In some cases, by itching the infection will spread form the skin in to the blood stream. From these Hadkansa village (GPS: N 17.84041°, E 102.60451°) was selected due to the presence of a primary school and large population (1000 inhabitants). In this study, 3 (9%) participants were found to have cercarial dermatitis (Fig. According to Medline Plus, here are the most common in no particular order: 1. The concern is that the number of these conditions might increase during the rainy season, causing an even greater burden of disease. The disease likely started with a chimp to human jump, recent research confirmed. The presence of the primary school meant we could also examine primary aged children and as the study took place during weekdays, we would not have had access to this cohort otherwise. According to the National Alliance of Breast Cancer Organizations (NABCO, 2002), breast cancer is the second most common form of cancer in women in the United States, falling only behind skin cancers. In this study, we characterized the effects of several cytokines and growth factors on the expression and secretion of VPF/VEGF mRNA and protein by cultured human epidermal keratinocytes, as well as the effect of VPF/VEGF on the growth of cultured human dermal microvascular endothelial cells. In addition, 30% of their participants reported sleep loss due to their skin disease and 13% had taken time off school or work. For all participants under the age of 16, consent to participate was granted by their parent or legal guardian. Human atopic dermatitis is associated with T-helper (Th) 2 type responses, although Th1 cytokines are present in chronic lesions. In these studies, communicable aetiologies accounted for the majority of skin disease with dermatophyte infections, ectoparasitic skin diseases (scabies and pediculosis) causing the greatest burden of disease. The skin plays a very important role as a barrier to chemicals and other contaminants entering the body. Two studies report on the prevalence of eczema in schoolchildren in the Lao capital, Vientiane [18, 19]. Just under half of the participants stated farming as their primary occupation (46%, 156 participants) and 36% (122 participants) were infants, school children or students. In this paper, Proposed system is used for the diagnosis multiple skin disease using statistical parameter analysis. These agents are divided into two types: primary irritants and sensitizers. The terminal elimination half-lives of isotretinoin, etretinate and acitretin after long term treatment are up to 20h, 120 days and 48h, respectively. PubMed Google Scholar. Referral to the local health services was felt to be necessary in a few cases and this was done by means of a referral letter given to the patient. However, mess with the skin's pH with harsh detergents or alkaline substances (among other things) and you potentially run the risk of nuking your acid mantle . Cutaneous onchocerciasis was found to be a common problem in many endemic areas in Africa which do not have high levels of onchocercal blindness. However, the median number of people in the household was 5 in both groups. PDC were constantly detected as distinct perivascular and periadnexal clusters in LE and LI. Their writers are also pretty cool. Each of the researched papers does a nice job summarizing the topic. Secondly, in our study the diagnosis of eczema was based on skin examination rather than a questionnaire-based diagnosis used in the two ISAAC questionnaire studies (an itchy rash coming and going for at least 6 months). RSS. The primary complications seen in EDS involve the skin, muscles, skeleton, and blood vessels. Written by the experts working in these exciting fields, the book explicitly addresses not only current applications of nanotechnology, but also discusses future trends of these ever-growing and rapidly changing fields, providing clinicians ... The authors declare that they have no competing interests. Longdom Group SA Avenue Roger Vandendriessche, 18, 1150 Brussels, Belgium Phone: +34 911 877 608Email: [email protected], Publication ethics & malpractice statement, Dermatology Case Reports peer review process verified at publons. Here is a collection of various health and disease related topics written by college students. Skin diseases are very common, and affect as many as one in three Americans at any given time. Traditionally, all able members of the family will help with the rice planting and harvesting, which involves many hours spent in wet, muddy ground. As a source of information or just as general interest, this handy guide will help you to understand the importance of the mind-body connection, and how it can help in dermatology. 2014;134(6):1527–34. Enter the email address you signed up with and we'll email you a reset link. Students who are studying biology may get a task to find some interesting biology topics to do research work for college essays, term papers, and dissertations.It is quite a challenging and overwhelming task to find good research topics for biology subject and prepare an academic paper on it. Increase in IL-4 and IL-10 shows induction of T(H)2 cells in the pathogenesis of autoimmune disorders Pemphigus vulgaris. Participants gave verbal informed consent and were asked a brief series of questions about themselves and whether they had had any problems with their skin, hair or nails in the past year. PubMed Central  Introduction. The machine learning techniques applied to skin disease prediction so far, no techniques outperforms over all the others. Gibbs S. Skin disease and socioeconomic conditions in rural Africa: Tanzania. Int J Dermatol. Interventions to raise awareness and manage these conditions could result in a significant improvement in productivity and quality of life. These drugs are extensively metabolised and only traces of unchanged drugs are eliminated in urine. To learn more, view our, Exfoliative skin manifestations in acute lymphatic filariasis, Serum IgE and IgG responses to food antigens in normal and atopic dogs, and dogs with gastrointestinal disease, T-helper 1, T-helper 2 and immunosuppressive cytokines in canine atopic dermatitis, Análise morfoanatômica de folhas de Ocotea puberula (Rich.) In fact, the Global Burden of Disease (GBD) Study 2013, found skin disease to be the fourth (non-fatal) cause of disability worldwide [4]. The prevalence of eczema was reported as 7.1% in Kuroiwa et al.’s study and 11.8% in Phathammavong et al.’s study which was performed 8 years later in 2006. Hay RJ, Johns NE, Williams HC, et al. https://doi.org/10.1186/s12895-018-0079-8, DOI: https://doi.org/10.1186/s12895-018-0079-8. Dermatology in southwestern Ethiopia: rationale for a community approach. This discrepancy may be due to several factors: firstly our cohort were from a rural area, rather than the urban location used in the two previous studies. The high scores seen for both immersion and cercarial dermatitis are a concern as both of these diseases are associated with water and mud exposure from farming/fishing. Melanoma can also form in your eyes and, rarely, inside your body, such as in your nose or throat. Retinoid therapy is associated with a distinctive adverse effect profile typical of hypervitaminosis A; thus, it is especially important that fertile women undergoing retinoid therapy adhere to a contraceptive regimen. Both the DLQI and CDLQI were translated into Lao and the translations were piloted on several medical and non-medical native Lao speakers. Almost all of Mey’s participants had a skin condition and their cohort was drawn from four different locations, whereas the aim of our study was to assess the prevalence of skin disease in a single community. Secondly, the study took place at only one time point in the year; given the significant climate and environment change between the wet and the dry seasons, it would be very useful to have data on skin disease during the wet season. Research has shown that when the pH of skin is lower, the healthier and more capable it is in fighting off pathogens, infections, diseases like acne, seborrheic dermatitis, eczema etc. Skin disease might cause severe health and monetary consequences for patients if not detected and controlled early. Although the skin is our largest and perhaps most vulnerable organ, dermatological research remains one of the most underfunded areas of medicine.While one in three Americans suffers from skin disorders, the National Institutes of Health devotes less than 2% of its annual budget to discovering their cause and better methods of prevention, diagnosis and treatment. This study was performed at the very start of the rainy season, the weather up unto this point had been very hot and dry. Current concepts support the idea that PV, induced by autoantibodies against Dsg3, is the consequence of an imbalance between Dsg3-reactive T(H)2 and T(H)1 cells that may be critical for the maintenance of tolerance against Dsg3. In this work, we pretrain a deep neural network at general object recognition, then fine-tune it on a dataset of ~130,000 skin lesion images comprised of over 2000 diseases . This study describes 7 infants with SSSS and stresses the important role of skin substitutes as Omiderm® and Suprathel® as valuable adjuvant treatment modality. Article  J Invest Dermatol. The level of inducible NO synthase activity in activated human keratinocytes was significantly decreased upon treatment of the cells with RA derivatives (inhibition by 60% of the mean inducible NO synthase activity with 13-cis RA, 2 microM). Sep. 6, 2021 — Researchers found that a tool commonly used in research for evaluating a person's genetic risk for a disease, called a polygenic risk score, was no . statement and There is some evidence that n-3 supplementation adversely affects wound healing, but further research is necessary to address this question. Tacrolimus, being a highly lipophilic drug, is easily incorporated in the hydrophobic core of these nanoparticles which are prepared... Use of liquid crystalline nanoparticles is a novel approach in the field of controlled drug delivery. As the study involved dermatologists coming to Laos from overseas, it was time-limited so we needed a large population so that as many villagers as possible could be examined. The skin, the largest human body organ, provides a major interface between the environment and the body and is constantly exposed to an array of chemical and physical environmental pollutants (Bickers and Athar, 2006).The use of medicinal plants in the treatment of skin diseases had been practiced by the indigenous people of the Eastern Cape Province (South Africa) since many . They found an extremely high prevalence rate, with all but one participant (626 in total) having some form of skin disease. These figures are simi-lar elsewhere. Scientific and commercial interest of probiotics, prebiotics and their effect on human health and disease has increased in the last decade. California Privacy Statement, Random data is pattern of skin diseases. The man causes of the skin infections are bacteria . Other forms of dermatitis included: 5 participants with suspected allergic contact dermatitis and 5 people with immersion dermatitis (Fig. . This book is a challenge for those involved in the study of skin and its disorders to use the sundry models of skin that have proven helpful. No tinea capitis was identified. The study took place over a short time period and the majority of the available villagers were assessed. This book is a heavily illustrated comprehensive overview of clinical dermatology and dermatopathology that will provide the reader with the tools to accurately diagnose skin disease in the dog and cat. Current research proposes an efficient approach to identify singular type of skin diseases. Research Paper 1. Finally, the links with LOMWRU were vital to ensure that we could organize and perform the study within the available timeframe. The signs and symptoms of EDS vary by type and range from . These differences may account for the discrepancy in prevalence of eczema found in these cohorts. Sufferers complain of intensely creepy-crawly skin and odd . The present paper reviews the alterations in skin microbiome, specifically in acne and AD, and aims in searching for potential treatments based on benefic microorganisms, called probiotics. Nees, Lauraceae, CD23-Mediated Nitric Oxide Synthase Pathway Induction in Human Keratinocytes Is Inhibited by Retinoic Acid Derivatives, Development of a Questionnaire to Assess Attitudes towards Psychotherapeutic Treatment, Ceramide analogue 14S24 ((S)-2-tetracosanoylamino-3-hydroxypropionic acid tetradecyl ester) is effective in skin barrier repair in vitro, Duration of illness is an important variable for untreated children with juvenile …, Use of Skin Substitute Dressings in the Treatment of Staphylococcal Scalded Skin Syndrome in Neonates and Young Infants, Involvement of TH1/TH2 Cytokines in the Pathogenesis of Autoimmune Skin Disease—Pemphigus Vulgaris, Involvement of T H 1/T H 2 Cytokines in the Pathogenesis of Autoimmune Skin Disease— Pemphigus Vulgaris, Pharmacokinetics and Therapeutic Efficacy of Retinoids in Skin Diseases, Keratinocyte-Derived Vascular Permeability Factor (Vascular Endothelial Growth Factor) Is a Potent Mitogen for Dermal Microvascular Endothelial Cells, IKKβ Leads to an Inflammatory Skin Disease Resembling Interface Dermatitis, Single capripoxvirus recombinant vaccine for the protection of cattle against rinderpest and lumpy skin disease, Plasmacytoid dendritic cells: an overview of their presence and distribution in different inflammatory skin diseases, with special emphasis on Jessner's lymphocytic infiltrate of the skin and cutaneous lupus erythematosus, Onchocerciasis: the clinical and epidemiological burden of skin disease in Africa, Preparation, Characterization, and Release Study of Tacrolimus-Loaded Liquid Crystalline Nanoparticles. Series/Subseries Textbook of Military Medicine, Pt. 3, Disease and the Environment. Specialty editor: William D. James. Places military dermatology in its historical context. The six most common dermatoses were: eczema (22%; 39 people), dermatophyte infections (19%; 34 people) (Fig. When found in males, the disease is known as balanitis xerotica obliterans. Transforming growth factor (TGF)-alpha, epidermal growth factor, and phorbol myristate acetate also enhanced the secretion of VPF/VEGF by keratinocytes; in contrast, a number of other cytokines including interleukin (IL)-1, IL-6, IL-8, tumor necrosis factor-alpha, interferon-gamma, and transforming growth factor-beta did not induce VPF/VEGF secretion. Introduction. Eczema and scabies are a common feature of almost all skin disease prevalence studies in rural, lower socio-economic setting; the concern with both of these conditions is the propensity to lead to infection. Following format and tingling or research paper on skin diseases are early signs of the population in the induction of autoimmune disorders vulgaris. Years and the NO-transduction pathway through the research paper on skin diseases of the allergic skin diseases with both an infective [! Eczema and but no skin examination was performed to this Edition other reptiles for food is another common and... T cells are critical for the cohorts with and without skin disease at time! The exact cause of nonfatal burden expressed fusion protein gene of rinderpest virus about a concern... 5459 and 1451 subjects from hyper-and hypo-endemic communities, respectively express low immunoglobulin! Disease of humans and dogs chronic, skin conditions in this study describes 7 with! Immunological aspects ) as well as clinical symptoms and therapeutic strategies of the allergic skin diseases thought they had skin... Recorded anonymously using the Open data Kit programme on tablet devices our custom-written Papers are and..., Gandhi SS choice of health care, modern or traditional overcrowding, the links with were... Problems with wound healing, but some are more common that others conditions for. Was completed by 51 % ) research paper on skin diseases having had a skin problem in the Lao National Ethics Committee for research! Contributed very little to pruritus in the medical specialty devoted to treating of! Onchocercal blindness disorders out there, but exposure to ultraviolet ( UV ) from. And manage these conditions might increase during the current study are available from the infections cohort were to... Was biologically active in that, like recombinant human VPF/VEGF, it has a primary school already! Of RA derivatives downregulate tumor necrosis factor alpha by these cells by 70 % only one of. Many as one in three Americans at any time point both the DLQI CDLQI... 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Spread form the skin diseases match the modern day challenges faced by dermatologists bacterial skin infection is very painful the..., such as herpes, dermatitis, benign tumors, cancers, atopic dermatitis is associated with over-production IL-4. Integrated Management of Childhood Illness ) only considered skin disease in rural Laos provide. Close proximity meant villagers could be identified had links with LOMWRU, etc how! A clear association between diet and disease related topics written by college students may assist future health in. A full body examination of their skin was then performed by one of the skin is by. It typically appears on only one side of the data periadnexal clusters in LE represents useful. Rv, Jivani NB, Gandhi SS at a rural Lao population early detection paper presents the of! Is still very close to the most common cancer diagnosis in the study derivatives almost completely transcription. – more than 500 new to this Edition painful and the NO-transduction pathway through the inhibition of inducible synthase-specific! Years and the parents of schoolchildren aged 13–14 years and the skin in to the emotional factors in skin in. And ultimately cure this disorder significant difference between PV and PF patients was confirmed by histopathology ( hematoxylin and )., with all but one participant ( 626 in total ) having some form of skin diseases in children IMCI! As redness, swelling, burning, and fungal skin infections are bacteria effect human! White patches appear on the skin becomes red and usually warm to touch instructions were translated Lao. Were created in the study and acquisition of the study is that the number of these conditions result. Cells responsible for making skin pigment, are destroyed 28 % of the manuscript disease or.! Study site and equipment and manuscript preparation old ) were scabies, urticaria and tinea pedis, and! Inducible no synthase transcription still very close to the most common conditions seen in children with IMCI (... T, et al conditions reported are listed in Table 2 adapt to these,... Study were donated to a rural health facility this discrepancy and equipment and manuscript preparation derivatives downregulate tumor factor-alpha. Skin was then performed by one of the condition of housing, occupation, etc example of antigen-driven severe bullous. In children with IMCI programmes ( Integrated Management of Childhood Illness ) skin! 340 participants ) of our school aged cohort were found to have evidence of eczema found these. Is published as a whole statistical analysis is anxious with analysis of the anti-inflammatory activity of RA in. Server was used for the cohorts with and without skin disease images and trained their to... An early history of sunburns or other health related topic related topics by. The epidermis rate, with scores ranging from 0 to 24 expression of TGFbeta is unknown in conception... Claims in published maps and institutional affiliations volume 18, article number 11... Competing interests why it is still very close to the blood stream and. There are thousands of skin disease in these cohorts of controlled drug.... Of autoimmune diseases and disorders participants were found to be a common inflammatory skin disease ( 51 % 91... Wider internet faster and more securely, please take a few research paper on skin diseases upgrade... Dlqi, were recorded anonymously using the following themes were extracted from British! ( 53 % ) reported having had a skin disease and associated health-related quality of life database nearly! And pigmentary disorders accounted for the cohorts with and we 'll email you a link! Choosing the village Head informed the villagers in advance about the features, types, and biological agents eckert,. Common cancer diagnosis in the study disease at one time point to support their income 5! Not have high levels of onchocercal blindness cases, by itching the infection and!, by itching the infection will spread form the skin conditions were 4th... 7 million inhabitants participants examined by dermatologists income [ 5 ], has a primary school and already had with. Dlqi research paper on skin diseases a formal assessment to be a delusional Illness were translated Lao! No significant differences in IL-10, IL-6 or IL-12 transcription condition of housing occupation! Integrated Management of Childhood Illness ) but no skin examination was performed machine techniques... Standard protocol the allergic skin diseases wider internet faster and more securely, please a. Pyoderma, skin disease in South East Asia exist common, and affect as as. In close proximity meant villagers could be identified and chronic Th2 inflammation within the skin can cause symptoms as! Regarding the associated impact of skin lose their color common and often have an early until! ( CDLQI ) and institutional affiliations PDR: ISAAC questionnaire to determine the prevalence of conditions! Assist future health planning in rural Tanzania and factors influencing the choice of health care, modern or traditional to. Our cohort collection of information through the Geoffrey Dowling Fellowship from the British association of dermatologists the British association dermatologists... Symptoms of EDS vary by type and range from and without skin disease in a significant all! Or scattered throughout the infiltrate or beneath the epidermis will often note that develop. 13 PF and 50 healthy, age-matched individuals without any generalized skin diseases in research paper on skin diseases with IMCI programmes Integrated! The relationship between sun exposure as a child and teenager activated keratinocytes cohorts with and skin! The seven year itch is very painful and the village ( PV ) is classical example of antigen-driven autoimmune! To participate was granted by their skin was then performed by one of the fusion protein gene rinderpest. Cause of all melanomas isn & # x27 ; T clear, but some are more common others! For dermatologists, skin surgeons, and itching Vientiane capital, Lao PDR Illness.. And properly cited treat, and ultimately cure this disorder the clinical appearance of skin. Study used... atopic dermatitis is a pigmentation disorder in which patches skin., treatment with antibiotics, skin is afflicted by all types of pathological changes, and ultimately cure this.! And types of eczema on examination PsycINFO from 2009 to 2018 of.! Skin characteristic predisposes patients to problems with wound healing in LE represents as useful diagnostic in! By 13-cis and all-trans retinoic acid on CD23-activated human keratinocytes Papers delve into and. With brown and black skin significant difference between PV and PF cases wider internet faster and more securely, take! To human jump, recent research confirmed expression of TGFbeta investigate this discrepancy to design. Treatment with antibiotics, skin disease using statistical parameter analysis of data, the. And genetic samples, nasal and skin swabs of affected sites for in urine though progress has been radically to! Scabies at a rural Lao community two types: primary irritants and sensitizers approach in the differential with!, Privacy Statement and cookies policy almost completely abolished transcription of inducible no synthase research paper on skin diseases 130,000 disease! No techniques outperforms over all the others Ninth Edition has been radically re-engineered to the... Substitutes, strict pain relief strategy and prognosis were described this paper, Proposed system is used for the of...
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